Experimental Infection of Sigmodon hispidus with Third-Stage Larvae of Angiostrongylus costaricensis

Publisher Website
Google Scholar
Abstract
Adult S. hispidus were given 50 3rd-stage larvae of A. costaricensis orally, i.p., s.c., and on abraded and unabraded skin. Larvae could not penetrate unbroken skin but established normal infections in the cecal vasculature by all other routes. Significantly more adults were recovered after oral and i.p. inoculation than s.c. or through abraded skin. In a single animal given larvae s.c., adult worms were recovered from the pulmonary arteries, an abnormal location for this species of metastronglyid nematode, which usually occurs in the ileocolic mesenteric arteries.