Primary Carcinoma of the Liver with Hypoglycemia

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Abstract
A survey of the literature reveals that cases of primary carcinoma of the liver are not uncommon, although the clinical diagnosis is difficult. It is infrequently made except by an exploratory operation or at post-mortem examination. The incidence of this lesion associated with hypoglycemia is, on the other hand, exceedingly rare. Boyce and McFetridge (1) in a recent review report 28 cases of carcinoma of the liver, making the total available in print at the present time well over six hundred. Yet among this number are only two cases of primary liver-cell carcinoma associated with hypoglycemia. One of these is reported by Crawford (2), the other by Elliott (3) and by Nadler and Wolfer (4). It is our purpose to review the literature on this subject briefly and to add to it a single case of this syndrome.

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