COMPARISON OF TWO LOTS OF IMMUNE SERUM GLOBULIN FOR PROPHYLAXIS OF INFECTIOUS HEPATITIS1

Abstract
Mosley, J. W. (N.GD.G, Atlanta, Ga. 30333), D. M. Reisler, D. Brachott, D. Roth and J. Weiser. Comparison of 2 lots of immune serum globulin for prophylaxis of infectious hepatitis. Amer. J. Epid., 1968, 87: 539–550.—Two lots of immune serum globulin which differed in several respects were compared for potency against infectious hepatitis. Their efficiencies for protection of exposed household contacts were 47 and 87 percent, respectively. This disparity is probably attributable, in large part, to differences in antibody concentrations and/or the fact that one preparation had undergone fragmentation into more rapidly excreted components.

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