INTRA-PERITONEAL IRRIGATION WITH POVIDONE-IODINE SOLUTION FOR THE PREVENTION OF INTRA-ABDOMINAL ABSCESSES IN THE BACTERIALLY CONTAMINATED ABDOMEN

  • 1 January 1979
    • journal article
    • research article
    • Vol. 148  (3) , 409-411
Abstract
A prospective randomized investigation was undertaken, involving 168 consecutive patients undergoing laparotomy for conditions accompanying bacterially contaminated peritoneal cavities, to evaluate the effectiveness of povidone-iodine irrigation of the peritoneum in preventing the development of intra-abdominal abscesses. In the treatment group irrigated with povidone-iodine solution, 0.1% available I, 1 of 80 patients had an abscess, 1.3%, while, in the saline solution irrigated control group, 9 of 88 patients had abscesses, 10.2%, P < 0.05. Although the serum I levels were elevated 24 h after i.p. irrigation with povidone-iodine solution, I levels returned to near normal by 72 h. Thyroxine levels showed no major changes. No complications resulting from the use of povidone-iodine were recognized.

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