Glomerulonephritis with - and 1C-globulin deposits induced in rats by mercuric chloride.

  • 1 November 1971
    • journal article
    • Vol. 65  (2) , 293-302
Abstract
Repeated subcutaneous injections of 0.15 or 0.25 mg/100 g of body weight of HgCl(2) may induce a membranous glomerulonephritis in rats. This glomerulonephritis with subepithelial deposits is similar, by electron microscopy and immunohistochemistry, to experimental chronic glomerulonephritis caused by immune complexes and to the human membranous glomerulonephritis.