Regiospecific Synthesis of 1,4,5-Trisubstituted-1,2,3-triazole via One-Pot Reaction Promoted by Copper(I) Salt
- 9 March 2005
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 2005 (8) , 1314-1318
- https://doi.org/10.1055/s-2005-861860
Abstract
A method for the regiospecific synthesis of 1,4,5-trisubstituted-1,2,3-triazole catalyzed by copper(I) iodide was developed. This is the first example of a regiospecific synthesis of 5-iodo-1,4-disubstituted-1,2,3-triazole, which can be further elaborated to a range of 1,4,5-trisubstituted-1,2,3-triazole derivatives.Keywords
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