Prognostic Factors in Stage I and II Non-Hodgkin's Lymphoma of Waldeyer's Ring
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in Acta Radiologica: Oncology
- Vol. 24 (2) , 153-158
- https://doi.org/10.3109/02841868509134379
Abstract
Stage I and II patients (69) treated for non-Hodgkin''s lymphoma of Waldeyer''s ring were retrospectively analyzed. Diffuse histiocytic lymphoma (Rappaport''s classification) was the most common histology (67%). Staging without laparotomy revealed 31 patients in stage I and 38 in stage II. Patients (65) received radiation therapy against involved or extended fields. In 43 patients adjuvant chemotherapy with single or multiple agents was given and 4 patients received only chemotherapy. A relapse occurred in 34 (49%) patients. The 5-yr relapse-free survival was 67% and 36% in stage I and stage II, respectively. Radiation doses of 50 Gy gave no recurrence within treated volumes. However, since relapse below the clavicles and especially below the diaphragm was common, the radiation doses did not seem important for reduction of the overall failure rate. In stage II, patients with a single neck node less than 5 cm in diameter seemed to have a better prognosis than patients with large or multiple neck nodes. In this non-randomized study adjuvant chemotherapy seemed to reduce the risk of relapse, especially in stage II patients.This publication has 12 references indexed in Scilit:
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