Comparative Effects of Seven Antidepressant Regimes on Appetite, Weight and Carbohydrate Preference

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Abstract
Appetite, weight, and preference for carbohydrate-containing food were followed in patients treated in double-blind trials of seven antidepressant regimes. Trimipramine and isocarboxazid combined had a significant effect in increasing appetite, carbohydrate preference, and weight; in patients who had lost appetite at presentation and were on this treatment, improvement in Hamilton score was linked to increase in weight.sbd.a finding not true of the other treatments.