Fluorescently tagged polymer bioconjugates from protein derived macroinitiators
- 29 September 2006
- journal article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 45,p. 4697-4699
- https://doi.org/10.1039/b609935a
Abstract
BSA and lysozyme have been transformed into macroinitiators for living radical polymerisation and used to produce well-defined bioconjugates which can be fluorescently labelled providing a versatile strategy for the preparation of bioconjugates which is complementary to traditional PEGylation.Keywords
This publication has 15 references indexed in Scilit:
- In Situ Preparation of Protein−“Smart” Polymer Conjugates with Retention of BioactivityJournal of the American Chemical Society, 2005
- Macromolecular design via reversible addition–fragmentation chain transfer (RAFT)/xanthates (MADIX) polymerizationJournal of Polymer Science Part A: Polymer Chemistry, 2005
- Fluorescently tagged star polymers by living radical polymerisation for mucoadhesion and bioadhesionReactive and Functional Polymers, 2005
- Design and Synthesis of N-Maleimido-Functionalized Hydrophilic Polymers via Copper-Mediated Living Radical Polymerization: A Suitable Alternative to PEGylation ChemistryJournal of the American Chemical Society, 2005
- α-Aldehyde Terminally Functional Methacrylic Polymers from Living Radical Polymerization: Application in Protein Conjugation “Pegylation”Journal of the American Chemical Society, 2004
- A new approach to bioconjugates for proteins and peptides (“pegylation”) utilising living radical polymerisationChemical Communications, 2004
- Polymer brushes via surface-initiated polymerizationsChemical Society Reviews, 2003
- Practical Synthetic Route to Functionalized Rhodamine DyesOrganic Letters, 2003
- Polyethylene glycol–superoxide dismutase, a conjugate in search of exploitationAdvanced Drug Delivery Reviews, 2002
- Atom Transfer Radical PolymerizationChemical Reviews, 2001