Studies on polypeptides XXXIV. Replacement of histidine‐2 in Luliberin (LH‐RH) by L‐homohistidine
- 1 January 1981
- journal article
- research article
- Published by Wiley in Recueil des Travaux Chimiques des Pays-Bas
- Vol. 100 (2) , 62-64
- https://doi.org/10.1002/recl.19811000206
Abstract
[Homohistidine2]LH‐RH has been synthesized by the solid phase method. NMR and CD spectra at two pH values have been measured. The remarkably low in vitro potency of the component, relative to LH‐RH, is discussed in terms of conformational differences.Keywords
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