Abstract
Cellulose phosphate cation-exchange paper has been investigated for its ability to separate biogenic amines. Descending chromatography with an ammonium acetate: isopropanol solvent mixture gave good separation of a number of these amines, including the principal catecholamines. The technique has the advantage of eliminating neutral and acidic compounds which may interfere in conventional partition methods. It has been applied to tissue extracts containing catecholamines.