Rush venom immunotherapy: a 3‐day programme for hymenoptera sting allergy

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Abstract
In a series of 102 patents consulting for allergic reactions following hymenoptera sting, 52 of them, who had experienced 1 or more severe systemic adverse reactions were selected for rush immunotherapy. The method used made it possible to attain the maintenance dose of 100 .mu.g venom in 3 days. Patient tolerance was excellent, no serious side-effect was observed; immunotherapy never had to be stopped. Clinical effectiveness seems to be satisfactory, since no abnormal reaction was reported in 7 patients who later were spontaneously stung and in 14 patients who received an induced insect sting. The level of IgG antivenom antibodies rose regularly from the 1st mo. onwards to remain at a stable level. Because of its safety and effectiveness, it appears that this method should be recommended for immunotherapy in patients who are allergic to Hymenoptera stings.

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