Modulation of Splicing in theDMDGene by Antisense Oligoribonucleotides
- 1 July 1997
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 16 (7-9) , 1665-1668
- https://doi.org/10.1080/07328319708006251
Abstract
Splicing of the DMD gene pre-mRNA is being examined as a model system to study the skipping of mutant exons, especially where disrupted translational reading frames are restored. Naturally-occurring examples and induced exon skipping by specific synthetic RNA oligonucleotides are under investigation.Keywords
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