Diuretics

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Abstract
DIURETIC agents afford an empirical approach to the management of patients with cardiac-failure, the nephrotic syndrome or liver disease, when these disorders lead to the retention of salt and water by the kidney, with the resultant accumulation of edema or ascites or both. It is beyond the scope of this paper to discuss the possible pathways whereby these diseases result in pathologic retention of salt and water by the kidney, but it should be emphasized that the pooling of extracellular fluid in the peritoneal cavity or the generalized interstitial spaces of the body may be a direct consequence of the . . .

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