Report of a Case of Pachyonychia Congenita

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Abstract
The following case of pachyonychia congenita is presented because administration of high doses of vitamin A and local treatment based on the physiology of the nail growth resulted in considerable clinical improvement. Report of a Case A 9-year-old Negro boy had had deformed nails almost from birth and later developed lesions on the glabrous skin and in the mouth. All 20 nails on fingers and toes were similarly affected. The nail appeared thick, and it protruded beyond the tip of the digit. It was attached normally in the proximal and lateral grooves and was arched transversely. The surface was smooth and shiny, and close inspection revealed that the nail plate itself seemed to be normal in thickness and consistency. It was being pushed upward by hard keratinous material collecting under it, so that the distal two-thirds of the dorsal surface of the nail formed a 30 to 40

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