THE DETECTION OF ESTROGENIC ACTIVITY IN TISSUES OF STEERS WHICH HAVE BEEN FED DIETHYLSTILBESTROL
- 1 December 1957
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry and Physiology
- Vol. 35 (12) , 1107-1112
- https://doi.org/10.1139/o57-126
Abstract
The immature female rat was used to detect estrogenic residues in the tissues of cattle fed a ration containing diethylstilbestrol. The criterion of response to the estrogen was the increase in uterine weight which resulted from the ingestion of the beef tissues. The weanling rat was twice as sensitive as the ovariectomized mouse to oral diethylstilbestrol. Significant levels of the estrogen were found in lean meat, liver, and kidney 24 hours after the removal of the diethylstilbestrol from the steers'' diet, but such residues could not be detected when this period was extended to 48 hours.This publication has 5 references indexed in Scilit:
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- Biological Assay of Beef Steer Carcasses for Estrogenic Activity Following the Feeding of Diethylstilbestrol at a Level of 10 Mg. Per Day in the RationJournal of Animal Science, 1956
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