Occurrence of Epithelial Atypia in 51 Indian Villagers with Oral Submucous Fibrosis
Open Access
- 1 March 1970
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 24 (2) , 253-257
- https://doi.org/10.1038/bjc.1970.28
Abstract
Fifty-three biopsies from the oral mucosa in 51 Indian villagers with oral submucous fibrosis have been studied for epithelial changes. A marked atrophy of the epithelium was found in 71.7%; the atrophic epithelium showed no rete ridges. The normally unkeratinized buccal mucosa revealed either ortho- or parakeratosis or hyperortho- or hyperparakeratosis in 48.0%. In one patient the histologic examination disclosed a squamous cell carcinoma. In 22.6% an epithelial atypia was found. The histologic features in these atypias are compared with those seen in leukoplakias from the same survey. The possible precancerous nature of submucous fibrosis is discussed.Keywords
This publication has 7 references indexed in Scilit:
- Oral epithelial changes in thirty indians with oral cancer and submucous fibrosisCancer, 1967
- Submucous fibrosis of the oral cavity. Histomorphological studies.British Journal of Cancer, 1966
- Frequency of oral submucous fibrosis in North India.1965
- Epithelial Changes in Oral Submucous FibrosisActa Odontologica Scandinavica, 1965
- Studies in Oral Leukoplakias. V. Clinical and Histologic Signs of MalignancyActa Odontologica Scandinavica, 1963
- Submucous fibrosis of the palate and pillars of the fauces.1962
- Cancer of the buccal mucosa.A clinical study of 650 cases in Indian patientsCancer, 1956