C3-Thia and C3-carba isosteres of a carbocyclic influenza neuraminidase inhibitor, (3R,4R,5S)-4-acetamido-5-amino-3-propoxyl-1-cyclohexene-1-carboxylic acid
- 22 July 1997
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 7 (14) , 1843-1846
- https://doi.org/10.1016/s0960-894x(97)00332-6
Abstract
No abstract availableKeywords
This publication has 5 references indexed in Scilit:
- Influenza Neuraminidase Inhibitors Possessing a Novel Hydrophobic Interaction in the Enzyme Active Site: Design, Synthesis, and Structural Analysis of Carbocyclic Sialic Acid Analogues with Potent Anti-Influenza ActivityJournal of the American Chemical Society, 1997
- Butane 2,3-Bisacetal Protection of Vicinal Diequatorial DiolsThe Journal of Organic Chemistry, 1996
- Structure of Influenza Virus Neuraminidase B/Lee/40 Complexed with Sialic Acid and a Dehydro Analog at 1.8-.ANG. Resolution: Implications for the Catalytic MechanismBiochemistry, 1994
- Molecular Modeling Studies on Ligand Binding to Sialidase from Influenza Virus and the Mechanism of CatalysisJournal of Medicinal Chemistry, 1994
- Fluorometric assay of neuraminidase with a sodium (4-methylumbelliferyl-α-d-N-acetylneuraminate) substrateAnalytical Biochemistry, 1979