Rapid Diagnosis of Herpetic Infections by Immunoperoxidase Method (With 1 color plate)

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Abstract
The PAP-(peroxidase-antiperoxidase)-immunohistochemical method was tested for rapid diagnosis on corneal specimens in clinically suspected herpetic disease. The method proved accurate, easy and useful in rapid diagnosis of corneal specimens from epithelial keratitis. Corneal buttons after keratoplasties for herpetic lesions were similarly tested for the presence of herpetic antigen. In 5 corneal buttons, antigen was found in 2 corneas with necrotizing keratitis; it was not noted in the 3 corneas opacified by disciform edema.

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