CLINICAL EFFECTS OF BUPRENORPHINE DURING AND AFTER OPERATION
- 1 October 1980
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 52 (10) , 1013-1019
- https://doi.org/10.1093/bja/52.10.1013
Abstract
The analgesic, respiratory and hormonal effects of 2 doses of buprenorphine were studied during and after operation in 20 patients undergoing total hip replacement. The drug provided analgesia of long duration. The analgesic and hormonal effects of the drug were greater after i.m. than after i.v. administration. The postoperative analgesic requirement of women was less than that of men. The pharmacodynamic differences shown between the sexes and between the 2 routes of administration are discussed in relation to the pharmacokinetics of the drug.This publication has 4 references indexed in Scilit:
- Epidural analgesia and the metabolic response to surgeryCanadian Journal of Anesthesia/Journal canadien d'anesthésie, 1979
- PLASMA FENTANYL CONCENTRATIONS AND CLINICAL OBSERVATIONS DURING AND AFTER OPERATIONBritish Journal of Anaesthesia, 1979
- A DOUBLE-BLIND COMPARISON OF MORPHINE AND BUPRENORPHINE IN THE PREVENTION OF PAIN AFTER OPERATIONBritish Journal of Anaesthesia, 1978
- EFFECT OF EPIDURAL ANALGESIA ON THE GLYCOREGULATORY ENDOCRINE RESPONSE TO SURGERYClinical Endocrinology, 1976