Serum‐Sulfated Lithocholate as an Indicator of Cholestasis During Parenteral Nutrition in Infants and Children
- 1 January 1982
- journal article
- Published by Wiley in Journal of Parenteral and Enteral Nutrition
- Vol. 6 (1) , 30-33
- https://doi.org/10.1177/014860718200600130
Abstract
Serum‐sulfated lithocholate concentrations were followed in 55 patients receiving parenteral nutrition. Elevation of serum lithocholate occurred in 18 (10/34 under 6 months of age, 8/21 older than 6 months). Serum sulfated lithocholate concentrations were a more sensitive indicator of cholestasis than either direct bilirubin or aminotransferases. The serum lithocholate concentrations in parenteral nutrition‐associated liver disease were similar to those seen in patients with known cholestasis.Keywords
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