CHORIOCARCINOMA - CAN WE AFFORD TO CURE CANCER

  • 1 January 1978
    • journal article
    • research article
    • Vol. 60  (1) , 36-41
Abstract
How management of patients with trophoblastic tumor depended on the acquisition of new knowledge and new drugs is demonstrated. Emphasis is put on the ability to detect early disease by biochemical markers and the ability to define on a multifactorial basis the resistance potential of the tumors. This provides a basis for stratification of treatment and the use of prophylactic chemotherapy to prevent cerebral metastases in certain patients. Although chemotherapy is often intensive and prolonged, there has so far been little evidence of long-term effects and many women had normal pregnancies subsequently, but the limitations of present data are discussed. The difficulties of matching available resources to society''s needs in the cancer field make it necessary to consider whether such treatment is unjustifiably expensive. For these tumors early diagnosis not only proves effective in the therapeutic terms but provides substantial financial savings. Screening programs for cancer cannot be accepted or rejected on principle. In judging them on their individual merits it is appropriate to anticipate interaction between earlier diagnosis and more effective drug treatment.