USE OF INTRAVENOUS FK506 TO TREAT ACUTE REJECTION IN SIMULTANEOUS PANCREAS-KIDNEY TRANSPLANT RECIPIENTS ON MAINTENANCE ORAL FK506

Abstract
Most recipients of simultaneous pancreas-kidney transplants experience acute rejection in the early postoperative course. We report our experience with four recipients of simultaneous pancreas-kidney transplants with acute rejection who were effectively treated with the combination of intravenous and oral FK506 therapy. This spared these patients an extra course of monoclonal or polyclonal antibody.