Effects of a new aldose reductase inhibitor, (2S, 4S)-6-fluoro-2′,5′-dioxospiro[chroman-4,4′-imidazolidine]-2-carboxamide (SNK-860), on the slowing of motor nerve conduction velocity and metabolic abnormalities in the peripheral nerve in acute streptozotocin-induced diabetic rats
- 1 October 1992
- journal article
- Published by Elsevier in Metabolism
- Vol. 41 (10) , 1081-1086
- https://doi.org/10.1016/0026-0495(92)90289-m
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Regeneration and Repair of Myelinated Fibers in Sural-Nerve Biopsy Specimens from Patients with Diabetic Neuropathy Treated with SorbinilNew England Journal of Medicine, 1988
- Role of sorbitol accumulation and myo-inositol depletion in paranodal swelling of large myelinated nerve fibers in the insulin-deficient spontaneously diabetic bio-breeding rat. Reversal by insulin replacement, an aldose reductase inhibitor, and myo-inositol.Journal of Clinical Investigation, 1987
- Reversal of deficits in axonal transport and nerve conduction velocity by treatment of streptozotocin-diabetic rats with myo-inositolExperimental Neurology, 1985
- Action of sorbinil in diabetic peripheral nerve. Relationship of polyol (sorbitol) pathway inhibition to a myo-inositol-mediated defect in sodium-potassium ATPase activityDiabetes, 1984
- Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphateNature, 1983
- Impaired rat sciatic nerve sodium-potassium adenosine triphosphatase in acute streptozocin diabetes and its correction by dietary myo-inositol supplementation.Journal of Clinical Investigation, 1983
- Immunohistochemical localization of aldose reductase. II. Rat eye and kidneyDiabetes, 1980
- Active Transport of Sodium and Potassium IonsNew England Journal of Medicine, 1980
- Diminished ouabain-sensitive, sodium-potassium ATPase activity in sciatic nerves of rats with streptozotocin-induced diabetesExperimental Neurology, 1976
- Effects of insulin and dietary myoinositol on impaired peripheral motor nerve conduction velocity in acute streptozotocin diabetes.Journal of Clinical Investigation, 1975