What's the Price of a Research Subject?

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Abstract
In their Sounding Board article on remuneration models for research subjects (July 15 issue),1 Dickert and Grady point out that payment of subjects is a common recruitment strategy, principally in trials sponsored by the pharmaceutical industry. The authors present a cogent argument based on ethical precepts for continuing this practice with both healthy volunteers and patient subjects. On review of three models (market, wage-payment, and reimbursement) for structuring payment to subjects, the authors advocate the uniform adoption of the wage-payment model as the most equitable and ethical approach.

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