Semisynthetic .BETA.-lactam antibiotics. 8. Structure-activity relationships of .ALPHA.-sulfocephalosporins.

Abstract
Synthesis and in vitro activity of a number of cephalosporins having .alpha.-sulfoacyl- or other acyl groups, e.g., .alpha.-carboxyacyl- and .alpha.-sulfoaminoacyl- at the 7-position and bearing a variety of heterocyclic thioether or pyridinium moieties at the 3-position are described.

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