Salicylate Therapy of Recurrent Calcium Urolithiasis

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Abstract
IT has been recognized for many years that the urine is a supersaturated solution so far as several relatively insoluble components are concerned when compared with a simple water solution of any one of them. The mutual increase of solubility that occurs in complex solutions, such as the urine, greatly reduces the degree of such supersaturation.1 Nevertheless, crystallization from normal urine is an everyday observation, and the formation of urinary-tract calculi indicates that the excretory load has exceeded the solubility of the stone components in the urinary mixture. Dilution of a complex solution may decrease the solubility of some of . . .