Cloning and Functional Expression of the Rat Brain KIR6.2 Channel.
- 1 January 1996
- journal article
- Published by Physiological Society of Japan in The Japanese Journal of Physiology
- Vol. 46 (6) , 491-495
- https://doi.org/10.2170/jjphysiol.46.491
Abstract
We obtained cDNA encoding KIR6.2 channel from the rat brain cDNA library. The reconstituted K+ channel with KIR6.2 and SUR1 genes retained properties similar to those reported in the native ATP-sensitive K+ channel including run-down and recovery of channel activity. When KIR6.2 was co-expressed with CFTR or MDR1, no K+ channel activity was recorded.Keywords
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