Demonstration of anti‐nuclear antibodies in fowl sera by immunofluorescence
- 1 July 1980
- journal article
- research article
- Published by Taylor & Francis in Avian Pathology
- Vol. 9 (3) , 377-383
- https://doi.org/10.1080/03079458008418421
Abstract
The occurrence of anti-nuclear antibodies in fowl sera is described. The anti-nuclear activity was demonstrated by immunofluorescence in a small percentage (3.9%) of the sera tested. The nuclei of cultured fowl and turkey cells were stained by anti-nuclear serum, whereas the nuclei of several mammalian tissues were not. Staining of chicken kidney cell nuclei by anti-nuclear serum conjugated with fluorescein isothiocyanate was blocked by unconjugated anti-nuclear serum but not by serum without anti-nuclear activity, indicating the specificity of the reaction. Confusion between anti-nuclear staining and specific viral [fowl adenovirus] staining is discussed, with the possible association of anti-nuclear factors with disease in birds.This publication has 6 references indexed in Scilit:
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- An antigen in normal avian cells which confuses virological and serological testsAvian Pathology, 1975
- Spontaneous Thyroiditis in the Obese Strain of ChickensThe Journal of Immunology, 1969
- Autoantibodies and DiseasePublished by Elsevier ,1964
- Incidence of the Anti-Nuclear Factor in Human SeraAnnals of the Rheumatic Diseases, 1960