S,S-DI-2-PYRIDYL DITHIOLOPHOSPHATE AS A KEY INTERMEDIATE IN THE PHOSPHORYLATION BY OXIDATION-REDUCTION CONDENSATION
- 5 February 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 5 (2) , 157-160
- https://doi.org/10.1246/cl.1976.157
Abstract
A key intermediate of phosphorylation by oxidation-reduction condensation which is useful for the preparation of various nucleotides was studied by means of 31P NMR using methanephosphonate as a model compound. The intermediate, S,S-di-2-pyridyl methanedithiolophosphonate, was formed quite rapidly by the reaction of methanephosphonic acid and triphenylphosphine-d15-2,2′-dithiodipyridine (PyS)2 in anhydrous pyridine and could be stored in solution.Keywords
This publication has 5 references indexed in Scilit:
- Solid phase peptide synthesis by oxidation-reduction condensationJournal of the American Chemical Society, 1975
- Solid Phase Peptide Synthesis by Oxidation-Reduction Condensation. Synthesis of LH–RH by Fragment Condensation on Solid SupportBulletin of the Chemical Society of Japan, 1973
- Synthesis of oligothymidylates and nucleoside cyclic phosphates by oxidation-reduction condensationJournal of the American Chemical Society, 1972
- Principles of Phosphorus Chemistry. XIV. Interchanges in Esters of Monophosphorus AcidsInorganic Chemistry, 1963
- Organic Phosphorus Compounds. I. The Conversion of the Chloroaluminate Complexes, [RPCl3][AlCl4], to Alkyl Alkylphosphonochloridates and Dialkyl AlkylphosphonatesJournal of the American Chemical Society, 1957