A cutaneous gene therapy approach to human leptin deficiencies: correction of the murine ob/ob phenotype using leptin‐targeted keratinocyte grafts
- 1 July 2001
- journal article
- Published by Wiley in The FASEB Journal
- Vol. 15 (9) , 1529-1538
- https://doi.org/10.1096/fj.01-0082com
Abstract
Leptin deficiency produces a phenotype of obesity, diabetes, and infertility in the ob/ob mouse. In humans, leptin deficiency occurs in some cases of congenital obesity and in lipodystrophic disord...Keywords
Funding Information
- Ministerio de Ciencia y Tecnología (PM98-0039, SAF 98-0047)
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