Performance of Today’s Cardiac Troponin Assays and Tomorrow’s
Open Access
- 1 June 2002
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 48 (6) , 809-810
- https://doi.org/10.1093/clinchem/48.6.809
Abstract
International scientific bodies currently recommend the use of cardiac troponins for the detection of myocardial necrosis (1)(2). Some troponin assays, however, are inadequately appraised before their introduction in clinical use (3). The Committee on Standardization of Markers of Cardiac Damage (C-SMCD) of the IFCC proposed quality specifications for cardiac troponin assays with the objectives to help assay manufacturers and clinical laboratories and to urge the scientific community to select and design research projects on the major issues in troponin determination (4). The study by Uettwiller-Geiger et al. (5) published in this month’s issue of Clinical Chemistry represents a good example that fulfills these suggestions.Keywords
This publication has 23 references indexed in Scilit:
- Recent approaches in standardization of cardiac markersClinica Chimica Acta; International Journal of Clinical Chemistry, 2001
- False-Positive Troponin I in a Patient with Acute Cholecystitis and Positive Rheumatoid Factor AssayCardiology, 2001
- Recent approaches to the standardization of cardiac markersScandinavian Journal of Clinical and Laboratory Investigation, 2001
- Extensive Troponin I and T Modification Detected in Serum From Patients With Acute Myocardial InfarctionCirculation, 2000
- Myocardial infarction redefined—a consensus document of The Joint European Society of Cardiology/American College of Cardiology committee for the redefinition of myocardial infarctionJournal of the American College of Cardiology, 2000
- Serum and Plasma Samples for ACS:Systems Cardiac MarkersClinical Chemistry, 2000
- Present issues in the determination of troponins and other markers of cardiac damageClinical Biochemistry, 2000
- Proposals from the IFCC Committee on Standardization of Markers of Cardiac Damage (C-SMCD): Strategies and concepts on standardization of cardiac marker assaysScandinavian Journal of Clinical and Laboratory Investigation, 1999
- Cardiac troponin I measurement with the ACCESS® immunoassay system: analytical and clinical performance characteristicsClinical Chemistry, 1998
- Troponin I is released in bloodstream of patients with acute myocardial infarction not in free form but as complexClinical Chemistry, 1997