Phosphorylation of Isocitrate Dehydrogenase of Escherichia coli
- 16 March 1979
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 203 (4385) , 1111-1112
- https://doi.org/10.1126/science.34215
Abstract
Addition of acetate to a stationary phase culture of Escherichia coli in glycerol mineral salts medium containing phosphorus-32-labeled orthophosphate results in rapid loss of isocitrate dehydrogenase activity and concomitant incorporation of phosphorus-32 into the enzyme. This is the first example of protein phosphorylation in a bacterium in which the endogenous substrate for the protein kinase has been identified.This publication has 20 references indexed in Scilit:
- Phosphorylated Proteins as Physiological EffectorsScience, 1978
- Concerted inhibition of NADP+-specific isocitrate dehydrogenase by oxalacetate and glyoxylate. I. Oxalomalate formation and stability, and nature of the enzyme inhibitionBiochimica et Biophysica Acta (BBA) - Enzymology, 1977
- Electrophoretic resolution of the ‘major outer membrane protein’ of Escherichia coli K12 into four bandsFEBS Letters, 1975
- Protein PhosphorylationAnnual Review of Biochemistry, 1975
- Reversible Inactivation of the Isocitrate Dehydrogenase of Escherichia coli ML308 during Growth on AcetateJournal of General Microbiology, 1975
- Solvent Systems for Hydrocarbon ResinsPublished by American Chemical Society (ACS) ,1973
- Protein kinase activity in cariogenic and non‐cariogenic oral streptococci: Activation and inhibition by cyclic AMPFEBS Letters, 1973
- NADP+-specific isocitrate dehydrogenase of Escherichia coli: I. Purification and characterizationBiochimica et Biophysica Acta (BBA) - Enzymology, 1972
- Protein-bound phosphorylthreonine in some tissues and organismsBiochimica et Biophysica Acta (BBA) - Protein Structure, 1970
- Regulation of Enzyme ActivityAnnual Review of Biochemistry, 1966