An A2Aadenosine receptor agonist, ATL313, reduces inflammation and improves survival in murine sepsis models
Open Access
- 20 October 2008
- journal article
- Published by Springer Nature in BMC Infectious Diseases
- Vol. 8 (1) , 141
- https://doi.org/10.1186/1471-2334-8-141
Abstract
The pathophysiology of sepsis is due in part to early systemic inflammation. Here we describe molecular and cellular responses, as well as survival, in A2A adenosine receptor (AR) agonist treated and untreated animals during experimental sepsis.Keywords
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