The gene for the familial form of incontinentia pigmenti (IP2) maps to the distal part of Xq28

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Abstract
Linkage data for familial incontinentia pigmenti (IP2) and 17 X chromosomal markers are reported. The linkage previously found between IP2 and the F8C locus Is confirmed (Z max = 11.85 at θ = 0.028). Linkage is established with distal markers DXS1108 (Z max = 10.06 at θ=0.00) and DXYS154 (Z= 9.07 at θ = 0.019). Multipoint analysis supports the distal localization of the IP2 gene with respect to the F8C locus.