Expression of the liver X receptor α and β in embryonic and adult mice
Open Access
- 9 March 2004
- journal article
- expressions
- Published by Wiley in The Anatomical Record Part A: Discoveries in Molecular, Cellular, and Evolutionary Biology
- Vol. 277A (2) , 312-316
- https://doi.org/10.1002/ar.a.20015
Abstract
We characterized the expression pattern of the nuclear receptors liver X receptor (LXR) α and β during mouse embryonic development and in adulthood by in situ hybridization experiments. LXRα and LXRβ are detected in the liver starting at 11.5 days postcoitum. Later, LXRα expression remains high in organs involved in lipid homeostasis, such as liver, intestine, and brown adipose tissue, whereas LXRβ is more ubiquitously expressed and enriched in tissues of neuronal and endocrine origin. Anat Rec Part A 277A:312–316, 2004.Keywords
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