Mortality of germfree and conventional mice after thermal trauma
- 1 August 1965
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 209 (2) , 365-370
- https://doi.org/10.1152/ajplegacy.1965.209.2.365
Abstract
Germfree mice survive thermal trauma better than conventional mice. Mortality during the first 48 hr (shock mortality) after severe (95 C) and moderate (70 C) hot-water burns was significantly less in germfree animals than in conventional controls. Mortality after 48 hr (late mortality) was significantly reduced in germfree mice after a moderate burn. These experiments, together with the previous finding of gram-negative bacteria in the tissues of conventional burned mice, demonstrate that bacteria cause death in burned mice during the shock period as well as later.Keywords
This publication has 0 references indexed in Scilit: