An immunogenic region within residues Val1670-Glu1684 of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor.
Open Access
- 1 April 1988
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 263 (11) , 5230-5234
- https://doi.org/10.1016/s0021-9258(18)60704-5
Abstract
No abstract availableThis publication has 33 references indexed in Scilit:
- The effect of thrombin on the complex between factor VIII and von Willebrand factorEuropean Journal of Biochemistry, 1987
- Construction and characterization of an active factor VIII variant lacking the central one-third of the moleculeBiochemistry, 1986
- Purification of human factor VIII:C and its characterization by Western blotting using monoclonal antibodiesBiochemistry, 1985
- Human factor VIII procoagulant protein. Monoclonal antibodies define precursor-product relationships and functional epitopes.Journal of Clinical Investigation, 1985
- Structure of human factor VIIINature, 1984
- Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycolurilBiochemical and Biophysical Research Communications, 1978
- Stabilization of Factor VIII in Plasma by the von Willebrand FactorJournal of Clinical Investigation, 1977
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976
- The Defect in Hemophilic and von Willebrand's Disease Plasmas Studied by a Recombination TechniqueJournal of Clinical Investigation, 1974
- Immunologic Studies in von Willebrand's DiseaseJournal of Clinical Investigation, 1972