COMPARATIVE-STUDY OF GASTROINTESTINAL BLEEDING DURING ADMINISTRATION OF KETOPROFEN AND NAPROXEN

  • 1 January 1977
    • journal article
    • research article
    • Vol. 6  (1) , 62-64
Abstract
The gastrointestinal blood losses arising after ketoprofen and naproxen therapy were studied in 12 male volunteers. A 51Cr-technique was used and the study was carried out using a double-blind crossover design. The median daily blood looses were 3.3 and 1.2 ml after ketoprofen and naproxen, respectively. Both preparations caused significantly increased gastrointestinal blood losses compared with preceding control periods, but there was no statistically significant difference between the 2 preparations. [Ketoprofen and naproxen are analgesics used in the treatment of rheumatoid arthritis.].

This publication has 1 reference indexed in Scilit: