Systolic Hypertension: Occurrence and Treatment in a Defined Community*

Abstract
Systolic hypertension, a disorder occurring predominantly in the elderly, is associated with an increased incidence of stroke and coronary artery disease. It may be a risk factor, and treatment is recommended. Treatment of systolic hypertension in a defined ambulatory population of 898 hypertensive subjects in a work-site program was studied. The systolic hypertension group (N = 39) was compared with a matched diastolic hypertension group and with a matched systolic/diastolic hypertension group (N = 39 each). Patients with systolic hypertension responded to standard treatment (chiefly diuretics), but less satisfactorily than did the patients with diastolic hypertension. Side effects or toxicity were uncommon and did not interfere with the therapeutic regimen. The ultimate value of such therapy in the prevention of vascular complications is not determined.

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