Acetate Metabolism: Effect of the Route of Tracer Dosage
- 1 September 1956
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 186 (3) , 393-396
- https://doi.org/10.1152/ajplegacy.1956.186.3.393
Abstract
Specially prepared adult rats were given tracer amounts of acetate-1-C14 intravenously or intraperitoneally. C14 incorporation into CO2 was followed on a time course basis and incorporation of the label into the fatty acid and cholesterol fractions of liver, gut, carcass and skin was determined. The dosage route was shown to affect the subsequent distribution of the label in the tissue lipids. Direct utilization of the acetate-1-C14 by tissues of the peritoneal space is considered to explain the high radioactivity of such tissues after i.p. dosage.Keywords
This publication has 5 references indexed in Scilit:
- LIPOGENESIS OF THE INTACT ALLOXAN-DIABETIC RATJournal of Biological Chemistry, 1954
- THE EFFECT OF FASTING UPON TISSUE LIPOGENESIS IN THE INTACT RATJournal of Biological Chemistry, 1954
- RATES OF METABOLISM OF ACETATE-1-C-14 IN TISSUES INVIVO1954
- Time Course of Lipide Labeling in the Intact Mouse and RatJournal of Biological Chemistry, 1953
- THE EFFECT OF FASTING UPON LIPOGENESIS IN THE INTACT RATJournal of Biological Chemistry, 1952