Dependence of Acute Radiosensitivity on Age in Adult Female Mouse

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Abstract
Female mice (75) were exposed to 100 r of X-radiation per day, 5 days/week, for the duration of life. The age of the animals at the beginning of the exposure to X-rays varied from 95 to 823 days. In the period from 100 to 600 days of age, the mean accumulated dose received prior to death showed little dependence on age, but in the period from 600 to 800 days of age, the dose received before death decreased rapidly. During the first half of adult life, there was no significant change in sensitivity to X-rays, but in late adult life, sensitivity in-creased.