Synthesis of model compounds for potential contrast agents containing phosphonate and peptide moieties
- 7 July 2000
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 16,p. 2831-2837
- https://doi.org/10.1039/a909086j
Abstract
The synthesis of dimethyl 2-acetoxy-2-(2,4-diiodo-5-aminophenyl)ethylphosphonate and dimethyl 2-acetoxy-2-(2,4,6-triiodo-3,5-diaminophenyl)ethylphosphonate is described. Several amido and peptidic derivatives of these two compounds were prepared. These products are composed of a combination of structural/functional moieties which pave the way for their potential application as non-ionic selective X-ray contrast agents.Keywords
This publication has 0 references indexed in Scilit: