The Oxidation of 14C-labelled Glucose by Chlorella vulgaris

Abstract
Glucose, either uniformly labelled with14C, or specifically labelled in the I, 2, or 6 position, was added to C. vulgaris. Radio-active carbon dioxide was produced initially ten times faster from glucose-I-14C than from glucose-6-14C. This difference was found with carbohydrate-starved cultures, exponentially growing cultures, and cultures assimilating ammonia or nitrate rapidly. A similar difference was also found with C. pyrenoidosa and Ankistrodesmus. 37 per cent. of the 14C added as glucose-1-14C to exponentially growing cells was recovered as carbon dioxide but generally the recovery was less than this. Only 5 per cent. of 14C added as glucose-6-14C was recovered as carbon dioxide. The specific activity of the carbon dioxide produced was considerably lower than that of the carbon in the added glucose.

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