Peptic Ulcer in Adults

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Abstract
Male peptic ulcer patients (34) were compared to a group of 37 healthy controls and a group of 36 hospitalized controls suffering from illnesses unrelated to the gastrointestinal tract. Patients and controls were submitted to the Eysenck Personality Inventory, Foulds'' Hostility Questionnaire, Langner''s 22-Item Questionnaire, the Hopkins Symptom Checklist, Zung''s Self-Rating Anxiety Scale, Spielberger''s State-Trait Anxiety Inventory, Zung''s and Beck''s Rating Scales for Depression, and the 43-item Life Event Inventory by Holmes and Rahe. All patients suffered from duodenal ulcer. The parameters that differentiated, to a statistically significant degree, the peptic ulcer patients from the groups of controls were: neuroticism, trait and state anxiety, guilt, general psychopathology, and stressful life events. More than 50% of the patients had at least one 1st-degree relative with peptic ulcer. Psychopathological, psychosocial, characterological and hereditary factors are important pathogenetic contributors in peptic ulcer.

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