Charged Amino Acids in the Sixth Transmembrane Helix of Multidrug Resistance Protein 1 (MRP1/ABCC1) Are Critical Determinants of Transport Activity
Open Access
- 1 November 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (44) , 41326-41333
- https://doi.org/10.1074/jbc.m206228200
Abstract
No abstract availableKeywords
This publication has 41 references indexed in Scilit:
- Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transportersToxicology, 2001
- Transport of the β-O-Glucuronide Conjugate of the Tobacco-specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the Multidrug Resistance Protein 1 (MRP1)Published by Elsevier ,2001
- Identification of Basic Residues Involved in Drug Export Function of Human Multidrug Resistance-associated Protein 2Journal of Biological Chemistry, 2000
- Helical Membrane Protein Folding, Stability, and EvolutionAnnual Review of Biochemistry, 2000
- Mutational Analysis of Basic Residues in the Rat Vesicular Acetylcholine TransporterPublished by Elsevier ,2000
- BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTERAnnual Review of Pharmacology and Toxicology, 1999
- ATP‐ and glutathione‐dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1British Journal of Pharmacology, 1999
- Charged Residues in Transmembrane Domains II and XI of a Vesicular Monoamine Transporter Form a Charge Pair That Promotes High Affinity Substrate RecognitionPublished by Elsevier ,1997
- Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell LineScience, 1992
- Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion SelectivityScience, 1991