A method of preserving a strain of the tubercle bacillus without having recourse to successive subcultivation or injection of the usual laboratory animals
- 1 November 1941
- journal article
- research article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 41 (3) , 289
- https://doi.org/10.1017/s0022172400012493
Abstract
It has been found that when a toad is injected subcutaneously (e.g. in the dorsal sac) with tubercle bacilli the micro-organisms disseminate but are stored in the liver mainly, where they multiply slowly without producing visible lesions and can be recovered by culture or injection of guinea-pigs after several years. Bovine tubercle bacilli were recovered in culture from the liver 1, 2 and over 3 years after subcutaneous injection and tubercle bacilli of avian type were still viable after 900 days in the liver.This publication has 0 references indexed in Scilit: