Clinical applications of angiogenic growth factors and their inhibitors
- 1 December 1999
- journal article
- review article
- Published by Springer Nature in Nature Medicine
- Vol. 5 (12) , 1359-1364
- https://doi.org/10.1038/70928
Abstract
Promoting the formation of new collateral vessels in ischemic tissues using angiogenic growth factors (therapeutic angiogenesis) is a an exciting frontier of cardiovascular medicine. Conversely, inhibition of the action of key regulators of angiogenesis, such as VEGF, constitutes a promising approach for the treatment of solid tumors and intraocular neovascular syndromes. These concepts are being tested now in clinical trials.Keywords
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