Amyloid Deposition in The Articular Structures of Akr Senescent Mice
Open Access
- 1 December 1981
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 24 (12) , 1540-1543
- https://doi.org/10.1002/art.1780241213
Abstract
Amyloid deposition in the articular structures occurred with high frequency in a strain of mice now being established as an animal model of senescence in this laboratory. The changes were most evident in the knee joint. Peripheral joints were always spared. The lesions appeared after 7 months of age, and the incidence reached 88% (7 of 8) in autopsied mice over 8 months of age. This is the first report of amyloid deposition in the joints of laboratory animals.This publication has 8 references indexed in Scilit:
- Amyloid Deposits and AmyloidosisNew England Journal of Medicine, 1980
- Local Amyloid Formation in the Hip Joint Capsule in OsteoarthritisActa Orthopaedica, 1973
- Occurrence of Amyloid in Rheumatoid Arthritis: Some ObservationsScandinavian Journal of Rheumatology, 1972
- Amyloid ArthropathyArthritis & Rheumatism, 1969
- HIGH-RESOLUTION ELECTRON MICROSCOPIC ANALYSIS OF THE AMYLOID FIBRILThe Journal of cell biology, 1967
- ON THE BINDING OF CONGO RED BY AMYLOIDJournal of Histochemistry & Cytochemistry, 1962
- The Relation between Amyloid and Ageing in Comparative PathologyGerontology, 1957
- Occurrence of Amyloid in Rheumatoid Arthritis: Some ObservationsActa Rheumatologica Scandinavica, 1955