Henoch-Schoenlein Purpura and Acute Interstitial Nephritis after Intravenous Vancomycin Administration in a Patient with a Staphylococcal Infection: CASE REPORT
- 1 January 1998
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Rheumatology
- Vol. 27 (3) , 233-235
- https://doi.org/10.1080/030097498440886
Abstract
We describe a case of Henoch-Schoenlein purpura, associated with oliguric acute renal failure due to acute interstitial nephritis histologically proven, in a patient with a staphylococcal chest infection. The clinical syndrome appeared twice after vancomycin administration and yielded on the withdrawal of the drug. As pathogenetic mechanism we propose an anaphylactoid reaction either to vancomycin or to a staphylococcal glycoprotein released after breakdown of the microbial cells caused by vancomycin.Keywords
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